Rumour mills have went into overdrive this week as speculation increases on the future of Katherine Heigl and T.R. Knight on medical drama, Grey’s Anatomy.

Sources have suggested for some time that the pair were getting itchy feet on the show, but now James Pickens Jr. has confirmed that both Heigl and Knight will be leaving in a US Weekly interview.

Pickens, who plays Dr Richard Webber on the show confirmed her departure and stated “Wherever Katherine goes, I wish her nothing but the best”. On the subject of T.R. Knight, he said “He’s going too. He just wanted to pursue other career paths”.